Many patients ask this question due to worries around post-transition regret. This is very rare and according to the World Professional Association of Transgender Health (WPATH) Standards of Care 8 (SOC 9), regret rates of gender-affirming care are as small as 1%. Destransition is similarly uncommon. Those who detransition do so for complex and individual reasons and should be met with empathy; most often, these have to do with weak support networks and few financial resources to pursue transition safely. Ultimately, it is normal to feel nervous about making a large change in your life. It is important to remember that for many transitioning brings measurable benefits to quality of life.