So far, there is little evidence linking saline or silicone breast implants to increased risk. Only 2% of all breast cancer occurs in the breast tissue of people designated male at birth, so the risk for breast cancer is very low for trans women and nonbinary people with or without breast implants. However, there is some scientific evidence that estrogen HRT can increase cancer risk. If you are over the age of 50 and have had HRT for 5 or more years, it’s recommended that you get an annual mammogram.